The oncoprotein p28(GANK) establishes a positive feedback loop in β-catenin signaling

p28(GANK) (also known as PSMD10 or gankyrin) is a novel oncoprotein that is highly expressed in hepatocellular carcinoma (HCC). Through its interaction with various proteins, p28(GANK) mediates the degradation of the tumor suppressor proteins Rb and p53. Although p53 was reported to downregulate β-c...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Dong, Li-wei, Yang, Guang-zhen, Pan, Yu-fei, Chen, Yao, Tan, Ye-xiong, Dai, Rong-yang, Ren, Yi-bin, Fu, Jing, Wang, Hong-yang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193485/
https://ncbi.nlm.nih.gov/pubmed/21691299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.103
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki