Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma

Oxidative stress status has a key role in hepatocellular carcinoma (HCC) development and progression. Normally, reactive oxygen species (ROS) levels are tightly controlled by an inducible antioxidant program that responds to cellular stressors. How HCC cells respond to excessive oxidative stress rem...

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Podrobná bibliografie
Vydáno v:J Exp Med
Hlavní autoři: Yang, Chun, Tan, Ye-xiong, Yang, Guang-zhen, Zhang, Jian, Pan, Yu-fei, Liu, Chen, Fu, Jing, Chen, Yao, Ding, Zhi-wen, Dong, Li-wei, Wang, Hong-yang
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854728/
https://ncbi.nlm.nih.gov/pubmed/27091842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151208
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