Cyclopropavir Inhibits the Normal Function of the Human Cytomegalovirus UL97 Kinase

Cyclopropavir (CPV) is active against human cytomegalovirus (CMV), as well as both variants of human herpesvirus 6 and human herpesvirus 8. The mechanism of action of CPV against CMV is similar to that of ganciclovir (GCV) in that it is phosphorylated initially by the CMV UL97 kinase, resulting in i...

Full description

Saved in:
Bibliographic Details
Main Authors: James, Scott H., Hartline, Caroll B., Harden, Emma A., Driebe, Elizabeth M., Schupp, James M., Engelthaler, David M., Keim, Paul S., Bowlin, Terry L., Kern, Earl R., Prichard, Mark N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186952/
https://ncbi.nlm.nih.gov/pubmed/21788463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00571-11
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items