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Cytomegalovirus UL97 Kinase Catalytic Domain Mutations That Confer Multidrug Resistance

Human cytomegalovirus UL97 kinase mutations that commonly confer ganciclovir resistance cluster in different parts of the gene than those conferring resistance to maribavir, an experimental UL97 kinase inhibitor. The drug resistance, growth, and autophosphorylation phenotypes of several unusual UL97...

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Bibliographic Details
Main Authors: Chou, Sunwen, Ercolani, Ronald J., Marousek, Gail, Bowlin, Terry L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697320/
https://ncbi.nlm.nih.gov/pubmed/23650173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00511-13
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