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Cytomegalovirus UL97 Mutations Affecting Cyclopropavir and Ganciclovir Susceptibility

Among the 7 most common UL97 mutations encountered in ganciclovir-resistant clinical cytomegalovirus isolates, the associated cyclopropavir cross-resistance varies from insignificant (L595S) to substantial (M460I and H520Q) as determined by recombinant phenotyping. Mutations M460I and H520Q were pre...

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Detalhes bibliográficos
Main Authors: Chou, Sunwen, Bowlin, Terry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019618/
https://ncbi.nlm.nih.gov/pubmed/21041510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01259-10
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