Cyclopropavir Inhibits the Normal Function of the Human Cytomegalovirus UL97 Kinase

Cyclopropavir (CPV) is active against human cytomegalovirus (CMV), as well as both variants of human herpesvirus 6 and human herpesvirus 8. The mechanism of action of CPV against CMV is similar to that of ganciclovir (GCV) in that it is phosphorylated initially by the CMV UL97 kinase, resulting in i...

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Main Authors: James, Scott H., Hartline, Caroll B., Harden, Emma A., Driebe, Elizabeth M., Schupp, James M., Engelthaler, David M., Keim, Paul S., Bowlin, Terry L., Kern, Earl R., Prichard, Mark N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2011
Ábhair:
Antiviral Agents
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186952/
https://ncbi.nlm.nih.gov/pubmed/21788463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00571-11
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