Human Cytomegalovirus UL97 Kinase Is Required for the Normal Intranuclear Distribution of pp65 and Virion Morphogenesis

Recombinant human cytomegaloviruses that do not express UL97 kinase activity exhibit a distinctive plaque morphology characterized by the formation of highly refractile bodies late in infection. These structures were also observed in infected cells treated with the UL97 kinase inhibitor maribavir. N...

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Detalhes bibliográficos
Main Authors: Prichard, Mark N., Britt, William J., Daily, Shannon L., Hartline, Caroll B., Kern, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316036/
https://ncbi.nlm.nih.gov/pubmed/16306620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.24.15494-15502.2005
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