Human Cytomegalovirus UL97 Kinase Activity Is Required for the Hyperphosphorylation of Retinoblastoma Protein and Inhibits the Formation of Nuclear Aggresomes

Cells infected with human cytomegalovirus in the absence of UL97 kinase activity produce large nuclear aggregates that sequester considerable quantities of viral proteins. A transient expression assay suggested that pp71 and IE1 were also involved in this process, and this suggestion was significant...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Prichard, Mark N., Sztul, Elizabeth, Daily, Shannon L., Perry, Amie L., Frederick, Samuel L., Gill, Rachel B., Hartline, Caroll B., Streblow, Daniel N., Varnum, Susan M., Smith, Richard D., Kern, Earl R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
Onderwerpen:
Virus-Cell Interactions
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346732/
https://ncbi.nlm.nih.gov/pubmed/18321963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02174-07
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items