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Cyclopropavir Susceptibility of Cytomegalovirus DNA Polymerase Mutants Selected after Antiviral Drug Exposure

Human cytomegalovirus (CMV) UL54 DNA polymerase (pol) mutants with known patterns of resistance to current antivirals ganciclovir (GCV), foscarnet (FOS), and cidofovir (CDV) were tested for cyclopropavir (CPV) susceptibility by a standardized reporter-based yield reduction assay. Exonuclease and A98...

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Detalhes bibliográficos
Main Authors: Chou, Sunwen, Marousek, Gail, Bowlin, Terry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256009/
https://ncbi.nlm.nih.gov/pubmed/21968367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05559-11
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