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Diverse Cytomegalovirus UL27 Mutations Adapt to Loss of Viral UL97 Kinase Activity under Maribavir
In vitro resistance to maribavir (MBV), a cytomegalovirus UL97 kinase inhibitor currently in clinical trials, is known to result from viral UL97 mutations that confer moderate to high-level resistance and UL27 mutations that confer low-level resistance. To add to the four reported UL27 mutations, cy...
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| Format: | Artigo |
| Jezik: | Inglês |
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American Society for Microbiology (ASM)
2009
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612169/ https://ncbi.nlm.nih.gov/pubmed/18981262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01177-08 |
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