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Differentiated Levels of Ganciclovir Resistance Conferred by Mutations at Codons 591 to 603 of the Cytomegalovirus UL97 Kinase Gene

Diagnostic mutations in the cytomegalovirus UL97 kinase gene are used to assess the level of associated ganciclovir resistance and therapeutic options. The best-known mutations at codons 460, 520, or 591 to 607 individually confer 5- to 10-fold-decreased ganciclovir susceptibility, except that a 3-f...

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書目詳細資料
發表在:J Clin Microbiol
Main Authors: Chou, Sunwen, Ercolani, Ronald J., Vanarsdall, Adam L.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483911/
https://ncbi.nlm.nih.gov/pubmed/28446569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00391-17
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