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Energetic Preference of 8-oxoG Eversion Pathways in a DNA Glycosylase

Base eversion is a fundamental process in the biochemistry of nucleic acids, allowing proteins engaged in DNA repair and epigenetic modifications to access target bases in DNA. Crystal structures reveal endpoints of these processes, but not the pathways involved in the dynamic process of base recogn...

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Detalhes bibliográficos
Main Authors: Bergonzo, Christina, Campbell, Arthur J., de los Santos, Carlos, Grollman, Arthur P., Simmerling, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173571/
https://ncbi.nlm.nih.gov/pubmed/21848286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja205142d
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