Base excision repair of 8-oxoG in dinucleosomes

In this work we have studied the effect of chromatin structure on the base excision repair (BER) efficiency of 8-oxoG. As a model system we have used precisely positioned dinucleosomes assembled with linker histone H1. A single 8-oxoG was inserted either in the linker or the core particle DNA within...

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Hlavní autoři: Menoni, Hervé, Shukla, Manu Shubhdarshan, Gerson, Véronique, Dimitrov, Stefan, Angelov, Dimitar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258150/
https://ncbi.nlm.nih.gov/pubmed/21930508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr761
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