Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal

One of the most abundant DNA lesions induced by oxidative stress is the highly mutagenic 8-oxoguanine (8-oxoG), which is specifically recognized by 8-oxoguanine DNA glycosylase 1 (OGG1) to initiate its repair. How DNA glycosylases find small non-helix-distorting DNA lesions amongst millions of bases...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Lebraud, Emilie, Pinna, Guillaume, Siberchicot, Capucine, Depagne, Jordane, Busso, Didier, Fantini, Damiano, Irbah, Lamya, Robeska, Elena, Kratassiouk, Gueorgui, Ravanat, Jean-Luc, Epe, Bernd, Radicella, J Pablo, Campalans, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498353/
https://ncbi.nlm.nih.gov/pubmed/32710616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa611
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky