Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein

We have investigated the effect of single amino acid substitutions of conserved arginines on the catalytic activities of the human Ogg1 protein (α-hOgg1-Ser(326)) (wild-type α-hOgg1). Mutant forms of hOgg1 with mutations Arg(46)→Gln (α-hOgg1-Gln(46)) and Arg(154)→His (α-hOgg1-His(154)) have previous...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Audebert, Marc, Radicella, J. Pablo, Dizdaroglu, Miral
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.14.2672
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