Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina

PURPOSE: The retina is highly exposed to oxidative stress due to the high level of oxygen consumption in this tissue and its exposure to light. The main DNA base lesion generated by oxygen free radicals is 8-oxoguanine (8-oxoG). However, its presence in retinal cells and the mechanisms underlying it...

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Main Authors: Bigot, Karine, Leemput, Julia, Vacher, Monique, Campalans, Anna, Radicella, J. Pablo, Lacassagne, Emmanuelle, Provost, Alexandra, Masson, Christel, Menasche, Maurice, Abitbol, Marc
Format: Artigo
Language:Inglês
Published: Molecular Vision 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690988/
https://ncbi.nlm.nih.gov/pubmed/19503746
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