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Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1)
The DNA base excision repair (BER) pathway, which utilizes DNA glycosylases to initiate repair of specific DNA lesions, is the major pathway for the repair of DNA damage induced by oxidation, alkylation, and deamination. Early results from clinical trials suggest that inhibiting certain enzymes in t...
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| Publié dans: | ACS Chem Biol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894821/ https://ncbi.nlm.nih.gov/pubmed/26218629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00452 |
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