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Repair of Oxidatively Induced DNA Damage by DNA Glycosylases: Mechanisms of Action, Substrate Specificities and Excision Kinetics

Endogenous and exogenous reactive species cause oxidatively induced DNA damage in living organisms by a variety of mechanisms. As a result, a plethora of mutagenic and/or cytotoxic products are formed in cellular DNA. This type of DNA damage is repaired by base excision repair, although nucleotide e...

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Detalhes bibliográficos
Publicado no:Mutat Res
Main Authors: Dizdaroglu, Miral, Coskun, Erdem, Jaruga, Pawel
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451025/
https://ncbi.nlm.nih.gov/pubmed/28342455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2017.02.001
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