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Phosphorylation of human oxoguanine DNA glycosylase (α-OGG1) modulates its function
Oxoguanine DNA glycosylase (OGG1) initiates the repair of 8-oxoguanine (8-oxoG), a major oxidative DNA base modification that has been directly implicated in cancer and aging. OGG1 functions in the base excision repair pathway, for which a molecular hand-off mechanism has been proposed. To date, onl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1143695/ https://ncbi.nlm.nih.gov/pubmed/15942030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki636 |
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