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Interaction with OGG1 Is Required for Efficient Recruitment of XRCC1 to Base Excision Repair and Maintenance of Genetic Stability after Exposure to Oxidative Stress

XRCC1 is an essential protein required for the maintenance of genomic stability through its implication in DNA repair. The main function of XRCC1 is associated with its role in the single-strand break (SSB) and base excision repair (BER) pathways that share several enzymatic steps. We show here that...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: Campalans, Anna, Moritz, Eva, Kortulewski, Thierry, Biard, Denis, Epe, Bernd, Radicella, J. Pablo
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387214/
https://ncbi.nlm.nih.gov/pubmed/25733688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00134-15
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