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Interaction with OGG1 Is Required for Efficient Recruitment of XRCC1 to Base Excision Repair and Maintenance of Genetic Stability after Exposure to Oxidative Stress

XRCC1 is an essential protein required for the maintenance of genomic stability through its implication in DNA repair. The main function of XRCC1 is associated with its role in the single-strand break (SSB) and base excision repair (BER) pathways that share several enzymatic steps. We show here that...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Campalans, Anna, Moritz, Eva, Kortulewski, Thierry, Biard, Denis, Epe, Bernd, Radicella, J. Pablo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387214/
https://ncbi.nlm.nih.gov/pubmed/25733688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00134-15
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