Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

Single-strand break repair (SSBR) and base excision repair (BER) of modified bases and abasic sites share several players. Among them is XRCC1, an essential scaffold protein with no enzymatic activity, required for the coordination of both pathways. XRCC1 is recruited to SSBR by PARP-1, responsible...

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Bibliographic Details
Main Authors:	Campalans, Anna, Kortulewski, Thierry, Amouroux, Rachel, Menoni, Hervé, Vermeulen, Wim, Radicella, J. Pablo
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2013
Subjects:	Genome Integrity, Repair and Replication
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3597691/ https://ncbi.nlm.nih.gov/pubmed/23355608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt025
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Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

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