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Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

Single-strand break repair (SSBR) and base excision repair (BER) of modified bases and abasic sites share several players. Among them is XRCC1, an essential scaffold protein with no enzymatic activity, required for the coordination of both pathways. XRCC1 is recruited to SSBR by PARP-1, responsible...

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Hlavní autoři:	Campalans, Anna, Kortulewski, Thierry, Amouroux, Rachel, Menoni, Hervé, Vermeulen, Wim, Radicella, J. Pablo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2013
Témata:	Genome Integrity, Repair and Replication
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3597691/ https://ncbi.nlm.nih.gov/pubmed/23355608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt025
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Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

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