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Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

Single-strand break repair (SSBR) and base excision repair (BER) of modified bases and abasic sites share several players. Among them is XRCC1, an essential scaffold protein with no enzymatic activity, required for the coordination of both pathways. XRCC1 is recruited to SSBR by PARP-1, responsible...

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Bibliografske podrobnosti
Main Authors: Campalans, Anna, Kortulewski, Thierry, Amouroux, Rachel, Menoni, Hervé, Vermeulen, Wim, Radicella, J. Pablo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597691/
https://ncbi.nlm.nih.gov/pubmed/23355608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt025
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