Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

Single-strand break repair (SSBR) and base excision repair (BER) of modified bases and abasic sites share several players. Among them is XRCC1, an essential scaffold protein with no enzymatic activity, required for the coordination of both pathways. XRCC1 is recruited to SSBR by PARP-1, responsible...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Campalans, Anna, Kortulewski, Thierry, Amouroux, Rachel, Menoni, Hervé, Vermeulen, Wim, Radicella, J. Pablo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597691/
https://ncbi.nlm.nih.gov/pubmed/23355608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt025
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares