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Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions
How DNA repair machineries detect and access, within the context of chromatin, lesions inducing little or no distortion of the DNA structure is a poorly understood process. Removal of oxidized bases is initiated by a DNA glycosylase that recognises and excises the damaged base, initiating the base e...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875005/ https://ncbi.nlm.nih.gov/pubmed/20071746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1247 |
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