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HECTD1 promotes base excision repair in nucleosomes through chromatin remodelling

Base excision repair (BER) is the major cellular DNA repair pathway that recognises and excises damaged DNA bases to help maintain genome stability. Whilst the major enzymes and mechanisms co-ordinating BER are well known, the process of BER in chromatin where DNA is compacted with histones, remains...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Bennett, Laura, Madders, Eleanor C E T, Parsons, Jason L
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026656/
https://ncbi.nlm.nih.gov/pubmed/31799632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1129
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