The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin

Efficient double-strand break repair in eukaryotes requires manipulation of chromatin structure. ATP-dependent chromatin remodelling enzymes facilitate different DNA repair pathways, during different stages of the cell cycle and in varied chromatin environments. The contribution of remodelling facto...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Kollárovič, Gabriel, Topping, Caitríona E, Shaw, Edward P, Chambers, Anna L
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038987/
https://ncbi.nlm.nih.gov/pubmed/31802118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1146
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