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HECTD1 promotes base excision repair in nucleosomes through chromatin remodelling

Base excision repair (BER) is the major cellular DNA repair pathway that recognises and excises damaged DNA bases to help maintain genome stability. Whilst the major enzymes and mechanisms co-ordinating BER are well known, the process of BER in chromatin where DNA is compacted with histones, remains...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Bennett, Laura, Madders, Eleanor C E T, Parsons, Jason L
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026656/
https://ncbi.nlm.nih.gov/pubmed/31799632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1129
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