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Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions

How DNA repair machineries detect and access, within the context of chromatin, lesions inducing little or no distortion of the DNA structure is a poorly understood process. Removal of oxidized bases is initiated by a DNA glycosylase that recognises and excises the damaged base, initiating the base e...

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Bibliografiska uppgifter
Huvudupphovsmän: Amouroux, Rachel, Campalans, Anna, Epe, Bernd, Radicella, J. Pablo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875005/
https://ncbi.nlm.nih.gov/pubmed/20071746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1247
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