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Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions

How DNA repair machineries detect and access, within the context of chromatin, lesions inducing little or no distortion of the DNA structure is a poorly understood process. Removal of oxidized bases is initiated by a DNA glycosylase that recognises and excises the damaged base, initiating the base e...

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Autors principals: Amouroux, Rachel, Campalans, Anna, Epe, Bernd, Radicella, J. Pablo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875005/
https://ncbi.nlm.nih.gov/pubmed/20071746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1247
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