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Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions

How DNA repair machineries detect and access, within the context of chromatin, lesions inducing little or no distortion of the DNA structure is a poorly understood process. Removal of oxidized bases is initiated by a DNA glycosylase that recognises and excises the damaged base, initiating the base e...

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書誌詳細
主要な著者: Amouroux, Rachel, Campalans, Anna, Epe, Bernd, Radicella, J. Pablo
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875005/
https://ncbi.nlm.nih.gov/pubmed/20071746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1247
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