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Interaction with OGG1 Is Required for Efficient Recruitment of XRCC1 to Base Excision Repair and Maintenance of Genetic Stability after Exposure to Oxidative Stress

XRCC1 is an essential protein required for the maintenance of genomic stability through its implication in DNA repair. The main function of XRCC1 is associated with its role in the single-strand break (SSB) and base excision repair (BER) pathways that share several enzymatic steps. We show here that...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Campalans, Anna, Moritz, Eva, Kortulewski, Thierry, Biard, Denis, Epe, Bernd, Radicella, J. Pablo
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387214/
https://ncbi.nlm.nih.gov/pubmed/25733688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00134-15
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