p53-independent functions of the p19(ARF) tumor suppressor

The p19(ARF) tumor suppressor antagonizes Mdm2 to induce p53-dependent cell cycle arrest. Individual TKO (triple knock out) mice nullizygous for ARF, p53, and Mdm2 develop multiple tumors at a frequency greater than those observed in animals lacking both p53 and Mdm2 or p53 alone, demonstrating that...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Weber, Jason D., Jeffers, John R., Rehg, Jerold E., Randle, David H., Lozano, Guillermina, Roussel, Martine F., Sherr, Charles J., Zambetti, Gerard P.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316930/
https://ncbi.nlm.nih.gov/pubmed/10995391
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares