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Tapping natural reservoirs of homing endonucleases for targeted gene modification
Homing endonucleases mobilize their own genes by generating double-strand breaks at individual target sites within potential host DNA. Because of their high specificity, these proteins are used for “genome editing” in higher eukaryotes. However, alteration of homing endonuclease specificity is quite...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156218/ https://ncbi.nlm.nih.gov/pubmed/21784983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107719108 |
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