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Tapping natural reservoirs of homing endonucleases for targeted gene modification
Homing endonucleases mobilize their own genes by generating double-strand breaks at individual target sites within potential host DNA. Because of their high specificity, these proteins are used for “genome editing” in higher eukaryotes. However, alteration of homing endonuclease specificity is quite...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156218/ https://ncbi.nlm.nih.gov/pubmed/21784983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107719108 |
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