Related homing endonucleases I-BmoI and I-TevI use different strategies to cleave homologous recognition sites

Por Edgell, David R., Shub, David A.
Publicado em 2001

Multiple Controls Regulate the Expression of mobE, an HNH Homing Endonuclease Gene Embedded within a Ribonucleotide Reductase Gene of Phage Aeh1

Por Gibb, Ewan A., Edgell, David R.
Publicado em 2007

An RNA Hairpin Sequesters the Ribosome Binding Site of the Homing Endonuclease mobE Gene

Por Gibb, Ewan A., Edgell, David R.
Publicado em 2009

Phage T4 mobE promotes trans homing of the defunct homing endonuclease I-TevIII

Por Wilson, Gavin W., Edgell, David R.
Publicado em 2009

Applications of Alternative Nucleases in the Age of CRISPR/Cas9

Por Guha, Tuhin K., Edgell, David R.
Publicado no Int J Mol Sci (2017)

Bacterial group I introns: mobile RNA catalysts

Por Hausner, Georg, Hafez, Mohamed, Edgell, David R
Publicado em 2014

Mobile DNA elements in T4 and related phages

Por Belfort Marlene, Gibb Ewan A, Edgell David R
Publicado em 2010-10-01

Barriers to Intron Promiscuity in Bacteria

Por Edgell, David R., Belfort, Marlene, Shub, David A.
Publicado em 2000

Mobile DNA elements in T4 and related phages

Por Edgell, David R, Gibb, Ewan A, Belfort, Marlene
Publicado em 2010

Learning to live together: mutualism between self-splicing introns and their hosts

Por Edgell, David R, Chalamcharla, Venkata R, Belfort, Marlene
Publicado em 2011

Distance determination by GIY-YIG intron endonucleases: discrimination between repression and cleavage functions

Por Liu, Qingqing, Derbyshire, Victoria, Belfort, Marlene, Edgell, David R.
Publicado em 2006

The monomeric GIY-YIG homing endonuclease I-BmoI uses a molecular anchor and a flexible tether to sequentially nick DNA

Por Kleinstiver, Benjamin P., Wolfs, Jason M., Edgell, David R.
Publicado em 2013

Perpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preference

Por Roy, Alexander C., Wilson, Geoffrey G., Edgell, David R.
Publicado no Nucleic Acids Res (2016)

A unified genetic, computational and experimental framework identifies functionally relevant residues of the homing endonuclease I-BmoI

Por Kleinstiver, Benjamin P., Fernandes, Andrew D., Gloor, Gregory B., Edgell, David R.
Publicado em 2010

Subunit and small-molecule interaction of ribonucleotide reductases via surface plasmon resonance biosensor analyses

Por Crona, Mikael, Furrer, Ernst, Torrents, Eduard, Edgell, David R., Sjöberg, Britt-Marie
Publicado em 2010

Divalent Metal Ion Differentially Regulates the Sequential Nicking Reactions of the GIY-YIG Homing Endonuclease I-BmoI

Por Kleinstiver, Benjamin P., Bérubé-Janzen, Wesley, Fernandes, Andrew D., Edgell, David R.
Publicado em 2011

Estimating the evidence of selection and the reliability of inference in unigenic evolution

Por Fernandes, Andrew D, Kleinstiver, Benjamin P, Edgell, David R, Wahl, Lindi M, Gloor, Gregory B
Publicado em 2010

Assembly of a fragmented ribonucleotide reductase by protein interaction domains derived from a mobile genetic element

Por Crona, Mikael, Moffatt, Connor, Friedrich, Nancy C., Hofer, Anders, Sjöberg, Britt-Marie, Edgell, David R.
Publicado em 2011

Insertion of a homing endonuclease creates a genes-in-pieces ribonucleotide reductase that retains function

Por Friedrich, Nancy C., Torrents, Eduard, Gibb, Ewan A., Sahlin, Margareta, Sjöberg, Britt-Marie, Edgell, David R.
Publicado em 2007

Monomeric site-specific nucleases for genome editing

Por Kleinstiver, Benjamin P., Wolfs, Jason M., Kolaczyk, Tomasz, Roberts, Alanna K., Hu, Sherry X., Edgell, David R.
Publicado em 2012