Comparison of the Safety and Pharmacokinetics of ST-246® after IV Infusion or Oral Administration in Mice, Rabbits and Monkeys

BACKGROUND: ST-246® is an antiviral, orally bioavailable small molecule in clinical development for treatment of orthopoxvirus infections. An intravenous (IV) formulation may be required for some hospitalized patients who are unable to take oral medication. An IV formulation has been evaluated in th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chen, Yali, Amantana, Adams, Tyavanagimatt, Shanthakumar R., Zima, Daniela, Yan, X. Steven, Kasi, Gopi, Weeks, Morgan, Stone, Melialani A., Weimers, William C., Samuel, Peter, Tan, Ying, Jones, Kevin F., Lee, Daniel R., Kickner, Shirley S., Saville, Bradley M., Lauzon, Martin, McIntyre, Alan, Honeychurch, Kady M., Jordan, Robert, Hruby, Dennis E., Leeds, Janet M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156126/
https://ncbi.nlm.nih.gov/pubmed/21858040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023237
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge