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Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ(1) receptors
To identify the ligands for σ(1) receptors that are potent and selective, the analogues of prezamicol and trozamicol scaffolds of carbonyl-containing vesicular acetylcholine transporter (VAChT) inhibitors were explored. Of the 23 analogues synthesized and tested, 5 displayed very high affinity for σ...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150604/ https://ncbi.nlm.nih.gov/pubmed/21732626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200203f |
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