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Synthesis and in Vitro Biological Evaluation of Carbonyl Group-Containing Inhibitors of Vesicular Acetylcholine Transporter
To identify selective high-affinity inhibitors of the vesicular acetylcholine transporter (VAChT), we have interposed a carbonyl group between the phenyl and piperidyl groups of the prototypical VAChT ligand vesamicol, and its more potent analogues benzovesamicol and 5-aminobenzovesamicol. Of 33 com...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853924/ https://ncbi.nlm.nih.gov/pubmed/20218624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9017916 |
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