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Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragments in Vivo

Identification of physiologically relevant substrates is still the most challenging part in protease research for understanding the biological activity of these enzymes. The zinc-dependent metalloprotease meprin β is known to be expressed in many tissues with functions in health and disease. Here, w...

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書誌詳細
主要な著者: Jefferson, Tamara, Čaušević, Mirsada, auf dem Keller, Ulrich, Schilling, Oliver, Isbert, Simone, Geyer, Rebecca, Maier, Wladislaw, Tschickardt, Sabrina, Jumpertz, Thorsten, Weggen, Sascha, Bond, Judith S., Overall, Christopher M., Pietrzik, Claus U., Becker-Pauly, Christoph
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149364/
https://ncbi.nlm.nih.gov/pubmed/21646356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252718
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