The Metalloprotease Meprin β Generates Amino Terminal-truncated Amyloid β Peptide Species

The amyloid β (Aβ) peptide, which is abundantly found in the brains of patients suffering from Alzheimer disease, is central in the pathogenesis of this disease. Therefore, to understand the processing of the amyloid precursor protein (APP) is of critical importance. Recently, we demonstrated that t...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bien, Jessica, Jefferson, Tamara, Čaušević, Mirsada, Jumpertz, Thorsten, Munter, Lisa, Multhaup, Gerd, Weggen, Sascha, Becker-Pauly, Christoph, Pietrzik, Claus U.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460434/
https://ncbi.nlm.nih.gov/pubmed/22879596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395608
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