The Metalloprotease Meprin β Generates Amino Terminal-truncated Amyloid β Peptide Species

The amyloid β (Aβ) peptide, which is abundantly found in the brains of patients suffering from Alzheimer disease, is central in the pathogenesis of this disease. Therefore, to understand the processing of the amyloid precursor protein (APP) is of critical importance. Recently, we demonstrated that t...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bien, Jessica, Jefferson, Tamara, Čaušević, Mirsada, Jumpertz, Thorsten, Munter, Lisa, Multhaup, Gerd, Weggen, Sascha, Becker-Pauly, Christoph, Pietrzik, Claus U.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460434/
https://ncbi.nlm.nih.gov/pubmed/22879596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395608
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