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Meprin Metalloproteases Inactivate Interleukin 6
Meprins have been implicated in the pathogenesis of several inflammatory diseases, including inflammatory bowel disease, in which the cytokine IL-6 is a prominent effector molecule. Because IL-6 levels are elevated markedly in meprin α and α/β knockout mice in an experimental model of inflammatory b...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953271/ https://ncbi.nlm.nih.gov/pubmed/24474695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546309 |
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