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Activation of the epithelial sodium channel by the metalloprotease meprin β subunit

The Epithelial Na(+) Channel (ENaC) is an apical heteromeric channel that mediates Na(+) entry into epithelial cells from the luminal cell surface. ENaC is activated by proteases that interact with the channel during biosynthesis or at the extracellular surface. Meprins are cell surface and secreted...

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Detalhes bibliográficos
Main Authors: García-Caballero, Agustín, Ishmael, Susan S, Dang, Yan, Gillie, Daniel, Bond, Judith S, Milgram, Sharon L, Stutts, M Jackson
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052204/
https://ncbi.nlm.nih.gov/pubmed/20953144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.1.13759
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