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Activation of the epithelial sodium channel by the metalloprotease meprin β subunit

The Epithelial Na(+) Channel (ENaC) is an apical heteromeric channel that mediates Na(+) entry into epithelial cells from the luminal cell surface. ENaC is activated by proteases that interact with the channel during biosynthesis or at the extracellular surface. Meprins are cell surface and secreted...

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Библиографические подробности
Главные авторы: García-Caballero, Agustín, Ishmael, Susan S, Dang, Yan, Gillie, Daniel, Bond, Judith S, Milgram, Sharon L, Stutts, M Jackson
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052204/
https://ncbi.nlm.nih.gov/pubmed/20953144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.1.13759
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