Activation of the epithelial sodium channel by the metalloprotease meprin β subunit

The Epithelial Na(+) Channel (ENaC) is an apical heteromeric channel that mediates Na(+) entry into epithelial cells from the luminal cell surface. ENaC is activated by proteases that interact with the channel during biosynthesis or at the extracellular surface. Meprins are cell surface and secreted...

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Main Authors: García-Caballero, Agustín, Ishmael, Susan S, Dang, Yan, Gillie, Daniel, Bond, Judith S, Milgram, Sharon L, Stutts, M Jackson
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052204/
https://ncbi.nlm.nih.gov/pubmed/20953144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.1.13759
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