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Energetic and structural basis for activation of the epithelial sodium channel by matriptase

Limited proteolysis, accomplished by endopeptidases, is a ubiquitous phenomenon underlying the regulation and activation of many enzymes, receptors and other proteins synthesized as inactive precursors. Serine proteases are one of the largest and conserved families of endopeptidases involved in dive...

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Bibliografske podrobnosti
Main Authors: Kota, Pradeep, García-Caballero, Agustin, Dang, Hong, Gentzsch, Martina, Stutts, M. Jackson, Dokholyan, Nikolay V.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404201/
https://ncbi.nlm.nih.gov/pubmed/22471557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2014773
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