Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragments in Vivo

Identification of physiologically relevant substrates is still the most challenging part in protease research for understanding the biological activity of these enzymes. The zinc-dependent metalloprotease meprin β is known to be expressed in many tissues with functions in health and disease. Here, w...

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Bibliografiset tiedot
Päätekijät: Jefferson, Tamara, Čaušević, Mirsada, auf dem Keller, Ulrich, Schilling, Oliver, Isbert, Simone, Geyer, Rebecca, Maier, Wladislaw, Tschickardt, Sabrina, Jumpertz, Thorsten, Weggen, Sascha, Bond, Judith S., Overall, Christopher M., Pietrzik, Claus U., Becker-Pauly, Christoph
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Protein Synthesis and Degradation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149364/
https://ncbi.nlm.nih.gov/pubmed/21646356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252718
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