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Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase
The assembly-line architecture of polyketide synthases (PKSs) provides an opportunity to rationally reprogram polyketide biosynthetic pathways to produce novel antibiotics. A fundamental challenge toward this goal is to identify the factors that control the unidirectional channeling of reactive bios...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149197/ https://ncbi.nlm.nih.gov/pubmed/21563224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.652 |
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