Programming of Erythromycin Biosynthesis by a Modular Polyketide Synthase

Por Cane, David E.
Publicado em 2010

Geosmin Biosynthesis. Mechanism of the Fragmentation–Rearrangement in the Conversion of Germacradienol to Geosmin

Por Jiang, Jiaoyang, Cane, David E.
Publicado em 2007

Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone in Streptomyces coelicolor. Mechanism and Stereochemistry of the Enzymatic Formation of Epi-isozizaene

Por Lin, Xin, Cane, David E.
Publicado em 2009

Exploration and Mining of the Bacterial Terpenome

Por Cane, David E., Ikeda, Haruo
Publicado em 2011

Stereospecific Formation of Z-Trisubstituted Double Bonds by the Successive Action of Ketoreductase and Dehydratase Domains from trans-AT Polyketide Synthases

Por Xie, Xinqiang, Cane, David E.
Publicado no Biochemistry (2018)

Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis

Por Cane, David E., Watt, Rory M.
Publicado em 2003

Biochemistry and Molecular Genetics of the Biosynthesis of the Earthy Odorant Methylisoborneol in Streptomyces coelicolor

Por Wang, Chieh-Mei, Cane, David E.
Publicado em 2008

Genome Mining in Streptomyces coelicolor. Molecular Cloning and Characterization of a New Sesquiterpene Synthase

Por Lin, Xin, Hopson, Russell, Cane, David E.
Publicado em 2006

Revisiting the Modularity of Modular Polyketide Synthases

Por Khosla, Chaitan, Kapur, Shiven, Cane, David E.
Publicado em 2009

Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme

Por Jiang, Jiaoyang, He, Xiaofei, Cane, David E.
Publicado em 2007

Coupled Methyl-Group Epimerization and Reduction by Polyketide Synthase Ketoreductase Domains. Ketoreductase-Catalyzed Equilibrium Isotope Exchange

Por Garg, Ashish, Khosla, Chaitan, Cane, David E.
Publicado em 2013

The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism

Por Duan, Lian, Jogl, Gerwald, Cane, David E.
Publicado no J Am Chem Soc (2016)

Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases

Por Xie, Xinqiang, Khosla, Chaitan, Cane, David E.
Publicado no J Am Chem Soc (2017)

Structure-Based Dissociation of a Type I Polyketide Synthase Module

Por Chen, Alice Y., Cane, David E., Khosla, Chaitan
Publicado em 2007

Mechanism and Specificity of an Acyltransferase Domain from a Modular Polyketide Synthase

Por Dunn, Briana J., Cane, David E., Khosla, Chaitan
Publicado em 2013

Stereochemistry of Reductions Catalyzed by Methyl-Epimerizing Ketoreductase Domains of Polyketide Synthases

Por You, Young-Ok, Khosla, Chaitan, Cane, David E.
Publicado em 2013

Recognition of Acyl Carrier Proteins by Ketoreductases in Assembly Line Polyketide Synthases

Por Ostrowski, Matthew P., Cane, David E., Khosla, Chaitan
Publicado no J Antibiot (Tokyo) (2016)

Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade

Por Rynkiewicz, Michael J., Cane, David E., Christianson, David W.
Publicado em 2001

Role of Arginine-304 in the Diphosphate-Triggered Active Site Closure Mechanism of Trichodiene Synthase

Por Vedula, L. Sangeetha, Cane, David E., Christianson, David W.
Publicado em 2005

Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlF, a short-chain dehydrogenase from Streptomyces avermitilis, and identification of a...

Por You, Zheng, Omura, Satoshi, Ikeda, Haruo, Cane, David E.
Publicado em 2006