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Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases
S-Adenosyl methionine (SAM)-dependent C-methyltransferases are responsible for the C2-methylation of 3-ketoacyl-acyl carrier protein (ACP) intermediates to give the corresponding 2-methy-3-ketoacyl-ACP products during bacterial polyketide biosynthesis mediated by trans-AT polyketide synthases that l...
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| Опубликовано в: : | J Am Chem Soc |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499234/ https://ncbi.nlm.nih.gov/pubmed/28430424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02911 |
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