ロード中...
Coupled Methyl-Group Epimerization and Reduction by Polyketide Synthase Ketoreductase Domains. Ketoreductase-Catalyzed Equilibrium Isotope Exchange
Incubation of [2-(2)H]-(2S,3R)-2-methyl-3-hydroxypentanoyl-SACP ([2-(2)H]-1a) with the epimerizing ketoreductase domain EryKR1 in the presence of a catalytic amount NADP(+) (0.05 equiv) resulted in time-and cofactor-dependent washout of deuterium from 1a, as a result of equilibrium isotope exchange...
保存先:
| 主要な著者: | , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865775/ https://ncbi.nlm.nih.gov/pubmed/24161343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja408944s |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|