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Recognition of Acyl Carrier Proteins by Ketoreductases in Assembly Line Polyketide Synthases
Ketoreductases (KRs) are the most widespread tailoring domains found in individual modules of assembly line polyketide synthases (PKSs), and are responsible for controlling the configurations of both the α-methyl and β-hydroxyl stereogenic centers in the growing polyketide chain. Because they recogn...
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| Published in: | J Antibiot (Tokyo) |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963262/ https://ncbi.nlm.nih.gov/pubmed/27118242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2016.41 |
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