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Recognition of Acyl Carrier Proteins by Ketoreductases in Assembly Line Polyketide Synthases

Ketoreductases (KRs) are the most widespread tailoring domains found in individual modules of assembly line polyketide synthases (PKSs), and are responsible for controlling the configurations of both the α-methyl and β-hydroxyl stereogenic centers in the growing polyketide chain. Because they recogn...

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Detalhes bibliográficos
Publicado no:J Antibiot (Tokyo)
Main Authors: Ostrowski, Matthew P., Cane, David E., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963262/
https://ncbi.nlm.nih.gov/pubmed/27118242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2016.41
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