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Protein-Protein Recognition between Acyltransferases and Acyl Carrier Proteins in Multimodular Polyketide Synthases
Acyltransferase (AT) domains of multimodular polyketide synthases are the primary gatekeepers for stepwise incorporation of building blocks into a growing polyketide chain. Each AT domain has two substrates, an α-carboxylated CoA thioester (e.g. malonyl-CoA or methylmalonyl-CoA) and an acyl carrier...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805051/ https://ncbi.nlm.nih.gov/pubmed/19921859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901826g |
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