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Solution structure and proposed domain–domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase

Polyketides are a medicinally important class of natural products. The architecture of modular polyketide synthases (PKSs), composed of multiple covalently linked domains grouped into modules, provides an attractive framework for engineering novel polyketide-producing assemblies. However, impaired d...

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Main Authors: Alekseyev, Viktor Y., Liu, Corey W., Cane, David E., Puglisi, Joseph D., Khosla, Chaitan
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204127/
https://ncbi.nlm.nih.gov/pubmed/17893358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073011407
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